Representative Publications of the Osher Center Leadership


Vergara DM, Berrueta L, Carmody C, An X, Wayne PM, Zavacki AM, Langevin HM.Am J Establishment of a novel porcine model to study the impact of active stretching on a local Carrageenan-induced inflammation. Phys Med Rehabil. 2020 May 14. doi: 10.1097/ PHM.0000000000001465.

Beaton-Starr M, Rist PM, Connor JP, Wayne PM, Osypiuk K, Bernstein C.Headache. Development and Implementation of the Integrative Toolbox for Headache Management. 2020 Apr;60(4):771-775. doi: 10.1111/head.13743.

Connor J, Buring JE, Eisenberg DM, Osypiuk K, Davis RB, Wayne PM. Patient Disclosure of Complementary and Integrative Health Approaches in an Academic Health Center.Glob Adv Health Med. 2020 Mar 16;9:2164956120912730. doi: 10.1177/2164956120912730.

Wayne PM, Bernstein C, Kowalski M, Connor JP, Osypiuk K, Long CR, Vining R, Macklin E, Rist PM  The Integrative Migraine Pain Alleviation through Chiropractic Therapy (IMPACT) trial: Study rationale, design and intervention validation. Contemp Clin Trials Commun. 2020 Jan 22;17:100531. doi: 10.1016/j.conctc.2020.100531.

Osypiuk K, Ligibel J, Giobbie-Hurder A, Vergara-Diaz G, Bonato P, Quinn R, Ng W, Wayne PM. Qigong Mind-Body Exercise as a Biopsychosocial Therapy for Persistent Post-Surgical Pain in Breast Cancer: A Pilot Study.Integr Cancer Ther. 2020 Jan-Dec;19:1534735419893766. doi: 10.1177/1534735419893766.

Wayne PM, Yeh GY, Mehta DH.A Spoonful of Mind-Body Medicine: If a Little Is Good, Is More Better? J Altern Complement Med. 2020 Jan;26(1):4-7. doi: 10.1089/acm.2020.29081.pmw.


Nusrat AZ, Majd I, Wayne PM. Integrative Medicine Is a Good Prescription for Patients and Planet.J Altern Complement Med. 2019 Dec;25(12):1151-1155. doi: 10.1089/acm.2019.0421.

Jacobson E, Conboy L, Tsering D, Shields M, McKnight P, Wayne PM, Schnyer R.Experimental Studies of Inter-Rater Agreement in Traditional Chinese Medicine: A Systematic Review. J Altern Complement Med. 2019 Nov;25(11):1085-1096. doi: 10.1089/acm.2019.0197.

Schnyer RN, McKnight P, Conboy LA, Jacobson E, Ledegza AT, Quilty MT, Davis RB, Wayne PM. Can Reliability of the Chinese Medicine Diagnostic Process Be Improved? Results of a Prospective Randomized Controlled Trial.J Altern Complement Med. 2019 Nov;25(11):1103-1108. doi: 10.1089/acm.2019.0260

You T, Ogawa EF, Thapa S, Cai Y, Yeh GY, Wayne PM, Shi L, Leveille SG.Effects of Tai Chi on beta endorphin and inflammatory markers in older adults with chronic pain: an exploratory study. Aging Clin Exp Res. 2019 Aug 20:10.1007/s40520-019-01316-1. doi: 10.1007/s40520-019-01316-1. Online ahead of print

Hwang I, Song R, Ahn S, Lee MA, Wayne PM, Sohn MK.Exploring the Adaptability of Tai Chi to Stroke Rehabilitation. Rehabil Nurs. 2019 Jul/Aug;44(4):221-229. doi: 10.1097/rnj.0000000000000110.

Wayne PM, Mehta DH, Yeh GY. “You Snooze, You Win!”-Minding Our Sleep. J Altern Complement Med. 2019 Jun;25(6):563-566. doi: 10.1089/acm.2019.29069.pwa.PMID: 31170006

Venkatraman A, Nandy R, Rao SS, Mehta DH, Viswanathan A, Jayasundar R .Tantra and Modern Neurosciences: Is there any Correlation? Neurol India. 2019 Sep-Oct;67(5):1188-1193. doi: 10.4103/0028-3886.271263.

Stephen AE, Mehta DH. Mindfulness in Surgery.Am J Lifestyle Med. 2019 Sep 16;13(6):552-555.      doi: 10.1177/1559827619870474. eCollection 2019 Nov-Dec.

Dubale BW, Friedman LE, Chemali Z, Denninger JW, Mehta DH, Alem A, Fricchione GL, Dossett ML, Gelaye B.Systematic review of burnout among healthcare providers in sub-Saharan Africa. BMC Public Health. 2019 Sep 11;19(1):1247. doi: 10.1186/s12889-019-7566-7.

Ingvar M, Mehta DH, Lekander M.The Challenge of the Many Choices in the Practice of Integrative Medicine. J Altern Complement Med. 2019 May;25(5):447-450. doi: 10.1089/acm.2019.29068.min.

Wayne PM, Yeh GY, Mehta DH.Minding the Mind-Body Literature: Burnout in Medicine and the Corporate Workforce.J Altern Complement Med. 2019 Jan;25(1):1-4. doi: 10.1089/acm.2018.29062.pmw

Hall KT, Battinelli E, Chasman DI, Ridker PM, Psaty BM, Rotter JI, Kaptchuk TJ, Tracy RP, Wassel CL, Mukamal KJ.Catechol-O-Methyltransferase and Cardiovascular Disease: MESA. J Am Heart Assoc. 2019 Dec 17;8(24):e014986. doi: 10.1161/JAHA.119.014986.

Wang RS, Croteau-Chonka DC, Silverman EK, Loscalzo J, Weiss ST, Hall KT. Pharmacogenomics and Placebo Response in a Randomized Clinical Trial in Asthma.Clin Pharmacol Ther. 2019 Dec;106(6):1261-1267. doi: 10.1002/cpt.1646.

Hall KT, Loscalzo J.Drug-Placebo Additivity in Randomized Clinical Trials. Clin Pharmacol Ther. 2019 Dec;106(6):1191-1197. doi: 10.1002/cpt.1626. Epub 2019 Oct 26

Hall KT, Kessler T, Buring JE, Passow D, Sesso HD, Zee RYL, Ridker PM, Chasman DI, Schunkert H.Genetic variation at the coronary artery disease risk locus GUCY1A3 modifies cardiovascular disease prevention effects of aspirin. Eur Heart J. 2019 Nov 1;40(41):3385-3392. doi: 10.1093/eurheartj/ehz384.

Hall KT, Loscalzo J, Kaptchuk T Systems pharmacogenomics – gene, disease, drug and placebo interactions: a case study in COMT. J.Pharmacogenomics. 2019 May;20(7):529-551. doi: 10.2217/pgs-2019-0001.

Morales-Quezada L, Martinez D, El-Hagrassy MM, Kaptchuk TJ, Sterman MB, Yeh GY. Neurofeedback impacts cognition and quality of life in pediatric focal epilepsy: An exploratory randomized double-blinded sham-controlled trial.Epilepsy Behav. 2019 Dec;101(Pt A):106570. doi: 10.1016/j.yebeh.2019.106570.

Holden SC, Manor B, Zhou J, Zera C, Davis RB, Yeh GY. Prenatal Yoga for Back Pain, Balance, and Maternal Wellness: A Randomized, Controlled Pilot Study.Glob Adv Health Med. 2019 Aug 26;8:2164956119870984. doi: 10.1177/2164956119870984.

You T, Ogawa EF, Thapa S, Cai Y, Yeh GY, Wayne PM, Shi L, Leveille SG Effects of Tai Chi on beta endorphin and inflammatory markers in older adults with chronic pain: an exploratory study..Aging Clin Exp Res. 2019 Aug 20:10.1007/s40520-019-01316-1. doi: 10.1007/s40520-019-01316-1.

Hall DL, Jimenez RB, Perez GK, Rabin J, Quain K, Yeh GY, Park ER, Peppercorn JM.Fear of Cancer Recurrence: A Model Examination of Physical Symptoms, Emotional Distress, and Health Behavior Change. J Oncol Pract. 2019 Sep;15(9):e787-e797. doi: 10.1200/JOP.18.00787.

Wells RE, Kerr C, Dossett ML, Danhauer SC, Sohl SJ, Sachs BC, Feeley JW, Wolkin J, Wall R, Kaptchuk T, Press DZ, Phillips RS, Yeh GY. Can Adults with Mild Cognitive Impairment Build Cognitive Reserve and Learn Mindfulness Meditation? Qualitative Theme Analyses from a Small Pilot Study.J Alzheimers Dis. 2019;70(3):825-842. doi: 10.3233/JAD-190191.

Ma Y, Wu CW, Peng CK, Ahn A, Bertisch SM, Lipsitz LA, Yeh GY, Manor B, Novak V, Hausdorff JM, Gow B, Wayne PM.Complexity-Based Measures of Heart Rate Dynamics in Older Adults Following Long- and Short-Term Tai Chi Training: Cross-sectional and Randomized Trial Studies. Sci Rep. 2019 May 16;9(1):7500. doi: 10.1038/s41598-019-43602-y

Conboy L, Krol J, Tomas J, Yeh GY, Wayne P, Salmoirago-Blotcher E. Tai Chi for heart attack survivors: qualitative insights. BMJ Support Palliat Care. 2019 Apr 4:bmjspcare-2018-001685. doi: 10.1136/bmjspcare-2018-001685.

Taylor RS, Walker S, Smart NA, Piepoli MF, Warren FC, Ciani O, Whellan D, O’Connor C, Keteyian SJ, Coats A, Davos CH, Dalal HM, Dracup K, Evangelista LS, Jolly K, Myers J, Nilsson BB, Passino C, Witham MD, Yeh GY; Impact of Exercise Rehabilitation on Exercise Capacity and Quality-of-Life in Heart Failure: Individual Participant Meta-Analysis. ExTraMATCH II Collaboration.J Am Coll Cardiol. 2019 Apr 2;73(12):1430-1443. doi: 10.1016/j.jacc.2018.12.072.

Litrownik D, Gilliam E, Berkowitz D, Yeh GY, Wayne PM.Reporting of Protocol Rationale and Content Validity in Randomized Clinical Trials of T’ai Chi: A Systematic Evaluation.J Altern Complement Med. 2019 Apr;25(4):370-376. doi: 10.1089/acm.2018.0389. Epub 2019 Mar 5.

Packiasabapathy S, Susheela AT, Mueller A, Patxot M, Gasangwa DV, O’Gara B, Shaefi S, Marcantonio ER, Yeh GY, Guided meditation as an adjunct to enhance postoperative recovery after cardiac surgery: study protocol for a prospective randomized controlled feasibility trial. Subramaniam B.Trials. 2019 Jan 11;20(1):39. doi: 10.1186/s13063-018-3103-8.PMID: 30635064

Hall KT, Buring JE, Mukamal KJ, Vinayaga Moorthy M, Wayne PM, Kaptchuk TJ, Battinelli EM, Ridker PM, Sesso HD, Weinstein SJ, Albanes D, Cook NR, Chasman DI. COMT and Alpha-Tocopherol Effects in Cancer Prevention: Gene-Supplement Interactions in Two Randomized Clinical Trials. J Natl Cancer Inst. (2019) doi: 10.1093/jnci/djy204.

Packiasabapathy S, Susheela AT, Mueller A, Patxot M, Gasangwa DV, O’Gara B, Shaefi S, Marcantonio ER, Yeh GY, Subramaniam B. Guided meditation as an adjunct to enhance postoperative recovery after cardiac surgery: study protocol for a prospective randomized controlled feasibility trial. Trials. (2019) 20:39.


Lo OY, Conboy LA, Rukhadze A, Georgetti C, Gagnon MM, Manor B, Lachman ME, Lipsitz LA, Wayne PM. In the Eyes of Those Who Were Randomized: Perceptions of Disadvantaged Older Adults in a Tai Chi Trial. Gerontologist. (2018) doi: 10.1093/geront/gny165.

Ruan QZ, Chen AD, Tran BNN, Epstein S, Fukudome EY, Tobias AM, Lin SJ, Lee BT, Yeh GY, Singhal D. Integrative Medicine in Plastic Surgery: A Systematic Review of Our Literature. Ann Plast Surg. (2018) doi: 10.1097/SAP.0000000000001676.

Rist PM, Hernandez A, Berstein C, Kowalski M, Osypiuk K, Vining R, Long CR, Goertz C, Song R, Wayne PM. The impact of spinal manipulation on migraine pain and disability: A systematic review and meta-analysis. Headache. (2018) In press.

Taylor RS, Walker S, Smart NA, Piepoli MF, Warren FC, Ciani O, O’Connor C, Whellan D, Keteyian SJ, Coats A, Davos CH, Dalal HM, Dracup K, Evangelista L, Jolly K, Myers J, McKelvie RS, Nilsson BB, Passino C, Witham MD, Yeh GY, Zwisler AO; ExTraMATCH II Collaboration.Impact of exercise-based cardiac rehabilitation in patients with heart failure (ExTraMATCH II) on mortality and hospitalisation: an individual patient data meta-analysis of randomised trials. Eur J Heart Fail. (2018) 20:1735-1743.

Conyers FG, Langevin HM, Badger GJ, and Mehta DH. Identifying Stress Landscapes in Boston Neighborhoods. Global Advances in Health and Medicine. (2018) 7:2164956118803058.

Hall DL, Luberto CM, Philpotts LL, Song R, Park ER, Yeh GYMind-body interventions for fear of cancer recurrence: A systematic review and meta-analysis. Psychooncology. (2018) 7:2546-2558.

Nelson-Wong E, Glinka M, Noguchi M, Langevin H, Badger GJ, Callaghan JP. Acute Surgical Injury Alters the Tensile Properties of Thoracolumbar Fascia in a Porcine Model. J Biomech Eng. (2018) 140(10). doi: 10.1115/1.4040452.

Chad-Friedman E, Pearsall M, Miller KM, Wheeler AE, Denninger JW, Mehta DH, Dossett ML. Total Lifestyle Coaching: A Pilot Study Evaluating the Effectiveness of a Mind-Body and Nutrition Telephone Coaching Program for Obese Adults at a Community Health Center. Glob Adv Health Med. (2018) 7:2164956118784902.

Basu-Ray I, Mehta DH, Shah S. Initial Treatment of Hypertension. New England Journal of Medicine. (2018) 378:1952-3.

Vergara-Diaz G, Osypiuk K, Hausdorff JM, Bonato P, Gow BJ, Miranda JG, Sudarsky LR, Tarsy D, Fox MD, Gardiner P, Thomas CA, Macklin EA, Wayne PMTai Chi for Reducing Dual-task Gait Variability, a Potential Mediator of Fall Risk in Parkinson’s Disease: A Pilot Randomized Controlled Trial. Global Advances in Health Medicine. (2018) 7:2164956118775385.

Wayne PM, Eisenberg DM, Osypiuk K, Gow BJ, Witt CM, Davis RB, Buring JE. A Multidisciplinary Integrative Medicine Team in the Treatment of Chronic Low-Back Pain: An Observational Comparative Effectiveness Study. Journal of Alternative and Complementary Medicine. (2018) (8):781-791.

Osypiuk K, Thompson E, Wayne PMCan Tai Chi and Qigong Postures Shape Our Mood? Toward an Embodied Cognition Framework for Mind-Body Research. Frontiers in Human Neuroscience. (2018) 12:174.

Wayne PM, Yeh G, Mehta DHMinding the mind-body literature: Aging and cognitive decline. Journal of Alternative and Complementary Medicine. (2018) 24:196-199.

Tick H, Nielsen A, Pelletier KR, Bonakdar R, Simmons S, Glick R, Ratner E, Lemmon RL, Wayne P, Zador V; Pain Task Force of the Academic Consortium for Integrative Medicine and Health. Evidence-based nonpharmacologic strategies for comprehensive pain care: the Consortium Pain Task Force white paper. Explore (NY). (2018) 14(3):177-211.

Ellis R, Rohan M, Fox J, Hitt J, Langevin H, Henry S. Ultrasound elastographic measurement of sciatic nerve displacement and shear strain during active and passive knee extension. Journal of Ultrasound in Medicine. (2018) 37(8):2091-2103.

You T, Ogawa EF, Thapa S, Cai Y, Zhang H, Nagae S, Yeh GYWayne PM, Shi L, Leveille SG. Tai Chi for older adults with chronic multisite pain: A randomized controlled pilot study. Aging Clinical and Experimental Research. (2018) 30(11):1335-1343.

Langevin HM, Wayne PM. What is the point? The problem with acupuncture research that no one wants to talk about. Journal of Alternative and Complementary Medicine. (2018) 24(3):200-207.

Cohen EM, Dossett ML, Mehta DH, Davis RB, Lee YC. Factors associated with insomnia and complementary medicine use in children: Results of a national survey. Sleep Medicine. (2018) 44:82-88.

Langevin HM, Bishop J, Maple R, Badger GJ, Fox JR.  Effect of stretching on thoracolumbar fascia injury and movement restriction in a porcine model. American Journal of Physical Medicine and Rehabilitation. (2018) 97:187–191.

Olenich S, Waterworth G, Badger GJ, Levy B, Israel E, Langevin HM. Flexibility and strength training in asthma: a pilot study. Journal of Asthma. (2018) 8:1-8.

Chaukos D, Chad-Friedman E, Mehta DH, Byerly L, Celik A, McCoy TH Jr, Denninger JW. SMART-R: A prospective cohort study of a resilience curriculum for residents by residents. Academic Psychiatry. (2018) 42:78-83.


Zia FZ, Olaku O, Bao T, Berger A, Deng G, Yin Fan A, Garcia MK, Herman PM, Kaptchuk TJ, Ladas EJ, Langevin HM, Lao L, Lu W, Napadow V, Niemtzow RC, Vickers AJ, Shelley Wang X, Witt CM, Mao JJ.  The National Cancer Institute’s Conference on Acupuncture for Symptom Management in Oncology: State of the science, evidence, and research gaps. Journal of the National Cancer Institute Monogram. (2017) 52. doi: 10.1093/jncimonographs/lgx005.

Song R, Ahn S, Lee M, Wayne PM, Sohn MK. Exploring the adaptability of Sun-style Tai Chi to stroke rehabilitation in Korean community dwelling stroke survivors: A mixed-methods feasibility study. Rehabilitation Nursing Journal. (2017) In Press. doi: 10.1097/mj.0000000000100.

Wayne PM, Lee MS, Osypiuk K, Ligibel J, Carlson LE, Song R.  Tai Chi and Qigong for cancer-related symptoms and quality of life: A systematic review and meta-analysis. Journal of Cancer Survivorship. (2017) doi: 10.1007/s11764-017-0665-5.

Salmoirago-Blotcher E, Wayne PM, Dunsiger S, Krol J, Breault C, Bock BC, Wu WC, Yeh GY. Tai Chi is a promising exercise option for patients with coronary heart disease declining cardiac rehabilitation. Journal of the American Heart Association. (2017) 6. doi: 10.1161/JAHA.117.006603.

Gow BJ, Hausdorff JM, Manor B, Lipsitz LA, Macklin EA, Bonato P, Novak V, Peng CK, Ahn AC, Wayne PMCan Tai Chi training impact fractal stride time dynamics, an index of gait health, in older adults? Cross-sectional and randomized trial studies. PLoS One. (2017) 12: e0186212. doi: 10.1371/journal.pone.0186212.

Wayne PM, Yeh G, Mehta DMinding the Mind-Bbody literature: Focusing on women’s health and pregnancy. The Journal of Alternative and Complementary Medicine. (2017) 23: 655-658.

Wayne PM, Gagnon MM, Macklin EA, Travison TG, Manor B, Lachman M, Thomas CP, Lipsitz LA. The Mind Body-wellness in supportive housing (Mi-WiSH) study: Design and rationale of a cluster randomized controlled trial of Tai Chi in senior housing. Contemporary Clinical Trials. (2017) 60:96-104.

Wayne PM, Mehta D, Yeh G. Minding the mind-body literature: Focusing on veterans. Journal of Alternative and Complementary Medicine. (2017) 23:401-404.

Mehta DIntegrative medicine and cardiovascular disorders. Primary Care. (2017) 44:351-367.

Carlson LE, Zelinski EL, Speca M, Balneaves LG, Jones JM, Santa Mina D, Wayne PM, Campbell TS, Giese-Davis J, Faris P, Zwicker J, Patel K, Beattie TL, Cole S, Toivonen K, Nation J, Peng P, Thong B, Wong R, Vohra S.  Protocol for the MATCH study (Mindfulness and Tai Chi for cancer health): A preference-based multi-site randomized comparative effectiveness trial (CET) of Mindfulness-Based Cancer Recovery (MBCR) vs. Tai Chi/Qigong (TCQ) for cancer survivors. Contemporary Clinical Trials. (2017) 59:64-76.

Song, RN, Grabowska W, Park M, Osypiuk K, Vergara-Diaz G, Bonato P, Hausdorff JM, Fox M, Sudarsky LR, Macklin EA, Wayne PM. The impact of Tai Chi and Qigong Mind-Body exercises on motor and non-motor function and quality of life in Parkinson’s disease: A systematic review and meta-analysis. Parkinsonism & Related Disorders. (2017) 41:3-13.

Yeung AS, Feng R, Kim DJH, Wayne PM, Yeh GY, Baer L, Lee OE, Denninger JW, Benson H, Fricchione GL, Alpert J, Fava M. A pilot, randomized controlled study of Tai Chi with passive and active controls in the treatment of depressed Chinese Americans. The Journal of Clinical Psychiatry. (2017) 78:e522-e528.

Kandula N, Ahmed M, Dodani S, Gupta L, Hore P, Kanaya A, Khowaja A, Mathur A, Mehta D, Misra R, Paracha M, Bharmal N, Aghhi M, Leng J, Gany F. Cardiovascular disease & cancer risk among South Asians: Impact of sociocultural influences on lifestyle and behavior. Journal of Immigrant and Minority Health. (2017) doi: 10.1007/s10903-017-0578-4.

Cohen EM, Dossett ML, Mehta DH, Davis RB, Lee YC. Factors associated with complementary medicine use in pediatric musculoskeletal conditions: Results from a national survey. Complementary Therapies in Medicine. (2017) 31:53-58.

Chaukos D, Chad-Friedman E, Mehta DH, Byerly L, Celik A, McCoy TH, Denninger JW. Risk and resilience factors associated with resident burnout. Academic Psychiatry. (2017) 41:189-194.

Langevin HM, Schnyer RN. Reconnecting the body in eastern and western medicine. Journal of Alternative and Complementary Medicine. (2017) 23:238-241.

Wayne PM, Gloria Y. Minding the Mind-Body literature: Focusing on children and youth. Journal of Alternative and Complementary Medicine. (2017) 23:155-157.

Stahl JE, Dossett ML, LaJoie AS, Denninger JW, Mehta DH, Goldman R, Fricchione GL, Benson H. Correction: Relaxation response and resiliency training and its effect on healthcare resource utilization. PLoS One. (2017) 12:e0172874. doi: 10.1371/journal.pone.0172874.

Xiong Y, Berrueta L, Urso K, Olenich S, Muskaj I, Badger GJ, Aliprantis A, Lafyatis R, Langevin HMStretching reduces skin thickness and improves subcutaneous tissue mobility in a murine model of systemic sclerosis. Frontiers in Immunology. (2017) 8:124. doi: 10.3389/fimmu.2017.00124.

Lauche R, Wayne PM, Fehr J, Stumpe C, Dobos G, Cramer H. Does postural awareness contribute to exercise-induced improvements in neck pain intensity? A secondary analysis of a randomized controlled trial evaluating Tai Chi and neck exercises. Spine. (2017) 42:1195-1200.

Cohen EM, Morley-Fletcher A, Mehta DH, Lee YC. A systematic review of psychosocial therapies for children with rheumatic diseases. Pediatric Rheumatology Online Journal. (2017) 15:6. doi: 10.1186/s1269016-0133-1.

Wayne PMehta D, Yeh G. Minding the Mind-Body literature: Frontiers in cancer treatment. Journal of Alternative and Complementary Medicine. (2017) 23:4-7.



Ma Y, Dong M, Zhou K, Mita C, Liu J, Wayne PMPublication trends in acupuncture research: A 20-year bibliometric analysis based on PubMed. PLoS One. (2016) 11:e0168123. doi: 10.1371/journal.pone.0168123.

Wayne PM, Yeh G, Mehta DMinding the Mind-Body literature. J Altern Complement Med. (2016) 22:849-852.

Eisenberg DM, Kaptchuk TJ, Post DE, Hrbek AL, O’Connor BB, Osypiuk K, Wayne PM, Buring JE, Levy DBEstablishing an Integrative Medicine program within an academic health center: Essential considerations. Acad Med. (2016) 91:1223-30.

Langevin HM, Keely P, Mao J, Hodge LM, Schleip R, Deng G, Hinz B, Swartz MA, de Valois BA, Zick S, Findley T. Connecting (T)issues: How research in fascia biology can impact Integrative Oncology. Cancer Res. (2016) 76:6159-6162.

Engell S, Triano JJ, Fox JR, Langevin HM, Konofagou EE. Differential displacement of soft tissue layers from manual therapy loading. Clin Biomech (Bristol, Avon). (2016) 33:66-72.

Bishop JH, Fox JR, Maple R, Loretan C, Badger GJ, Henry SM, Vizzard MA, Langevin HMUltrasound evaluation of the combined effects of thoracolumbar fascia injury and movement restriction in a porcine model. PLoS One. (2016) 11:e0147393. doi: 10.1371/journal.pone.0147393.

Berrueta L, Muskaj I, Olenich S, Butler T, Badger GJ, Colas RA, Spite M, Serhan CN, Langevin HMStretching impacts inflammation resolution in connective tissue. J Cell Physiol. (2016) 231:1621-7.

Dossett ML, Korzenik JR, Baim M, Denninger JW, Mehta DHA case report of improvement in Crohn’s Disease-related symptoms following participation in a comprehensive Mind-Body program. Glob Adv Health Med. (2016) 5:122-5.

MacPherson H, Hammerschlag R, Coeytaux RR, Davis RT, Harris RE, Kong JT, Langevin HM, Lao L, Milley RJ, Napadow V, Schnyer RN, Stener-Victorin E, Witt CM, Wayne PMUnanticipated insights into biomedicine from the study of acupuncture. J Altern Complement Med. (2016) 22:101-7.

Lauche R, Wayne PM, Dobos G, Cramer H. Prevalence, patterns, and predictors of T’ai Chi and Qigong use in the United States: Results of a nationally representative survey. J Altern Complement Med. (2016) 22:336-42.

Yeh GY, Chan CW, Wayne PM, Conboy L. The impact of Tai Chi exercise on self-efficacy, social support, and empowerment in heart failure: Insights from a qualitative sub-study from a randomized controlled trial. PLoS One. (2016) 11:e0154678. doi: 10.1371/journal.pone.0154678.

Lauche R, Stumpe C, Fehr J, Cramer H, Cheng YW, Wayne PM, Rampp T, Langhorst J, Dobos G. The effects of Tai Chi and neck exercises in the treatment of chronic nonspecific neck pain: A randomized controlled trial. J Pain. (2016) 17:1013-27.

Budhrani-Shani P, Berry DL, Arcari P, Langevin HWayne PMMind-Body exercises for nurses with chronic low back pain: An evidence-based review. Nurs Res Pract. (2016) 2016:9018036.

Yeh GY, Mu L, Davis RB, Wayne PMCorrelates of exercise self-efficacy in a randomized trial of Mind-Body exercise in patients with chronic heart failure. J Cardiopulm Rehabil Prev. (2016) 36:186-94.



Langevin HM, Schnyer R, MacPherson H, Davis R, Harris RE, Napadow V, Wayne PM, Milley RJ, Lao L, Stener-Victorin E, Kong JT, Hammerschlag R. Manual and electrical needle stimulation in acupuncture research: Pitfalls and challenges of heterogeneity. J Altern Complement Med. (2015) 21:113-28.

Jacobson EE, Meleger AL, Bonato P, Wayne PM, Langevin HM, Kaptchuk TJ, Davis RB. Structural integration as an adjunct to outpatient rehabilitation for chronic nonspecific low back pain: a randomized pilot clinical trial. Evid Based Complement Alternat Med. (2015) 2015:813418.

Wayne PM, Hausdorff JM, Lough M, Gow BJ, Lipsitz L, Novak V, Macklin EA, Peng CK, Manor B. Tai Chi training may reduce dual task gait variability, a potential mediator of fall risk, in healthy older adults: Cross-sectional and randomized trial studies. Front Hum Neurosci. (2015) 9:332.

Salmoirago-Blotcher E, Wayne PM, Bock BC, Dunsiger S, Wu W, Stabile L, Yeh G. Design and methods of the Gentle Cardiac Rehabilitation Study – A behavioral study of Tai Chi exercise for patients not attending cardiac rehabilitation. Contemp Clin Trials. (2015) 43:243-51.

Moy ML, Wayne PM, Litrownik D. Beach D, Klings ES, Davis EB, Yeh GY. Long-term Exercise After Pulmonary Rehabilitation (LEAP): Design and rationale of a randomized controlled trial of Tai Chi Contemporary Clinical Trials. (2015) 45:458-67.

Gow B, Peng CK, Wayne PM, Ahn A. Multiscale entropy analysis of center-of-pressure dynamics in human postural control: Methodological considerations.  Entropy. (2015) 17:7926–7947.

Walsh JN, Manor B,  Hausdorff J, Novak V, Lipsitz L, Gow B, Macklin EA, Peng CK,   Wayne PM.   Impact of short- and long-term Tai Chi Mind-Body exercise training on cognitive function in healthy adults: Results from a hybrid observational study and randomized trial. Global Adv Health Med. (2015) 4:38-48.

O’Connor B, Eisenberg DM, Buring JE, Liang C, Osypiuk K, Levy DBWayne PMWithin-team patterns of communication and referral in multimodal treatment of chronic low back pain patients by an integrative care team. Global Adv Health Med. (2015) 4:36-45.

Yang GY, Wang LQ, Ren J, Zhang Y, Li ML, Zhu YT, L Juo, Cheng YJ, Li WY, Wayne PM, Liu JP. Evidence base of clinical studies on Tai Chi: A bibliometric analysis. PLoS ONE. (2015) 10:e0120655. doi: 10.1371/journal.pone.0120655.

Miller KM, Chad-Friedman E, Haime V, Mehta DH, Lepoutre V, Gilburd D, Peltier-Saxe D, Lilley C, Benson H, Fricchione GL, Denninger JW, Yeung A. The effectiveness of a brief Mind-Body intervention for treating depression in community health center patients. Glob Adv Health Med. (2015) 4:30-5.

Sylvia LG, Bui E, Baier AL, Mehta DH, Denninger JW, Fricchione GL, Casey A, Kagan L, Park ER, Simon NM. Resilient warrior: A stress management group to improve psychological health in service members. Glob Adv Health Med. (2015) 4:38-42.

Stahl JE, Dossett ML, LaJoie AS, Denninger JW, Mehta DH, Goldman R, Fricchione GL, Benson H. Relaxation response and resiliency training and its effect on healthcare resource utilization. PLoS One. (2015) 10:e0140212. doi: 10.1371/journal.pone.0140212.

Scult M, Haime V, Jacquart J, Takahashi J, Moscowitz B, Webster A, Denninger JW, Mehta DHA healthy aging program for older adults: Effects on self-efficacy and morale. Adv Mind Body Med. (2015) 29:26-33.

Perez GK, Haime V, Jackson V, Chittenden E, Mehta DH, Park ER. Promoting resiliency among palliative care clinicians: Stressors, coping strategies, and training needs. J Palliat Med. (2015) 18:332-7.


Seminal Publications of the Osher Center for Integrative Medicine

Eisenberg DM, Kessler RC, Foster C, Norlock FE, Calkins DR, Delbanco TL. Unconventional medicine in the United States. Prevalence, costs, and patterns of use. N Engl J Med. (1993) 328:246-52.

Eisenberg DM, Davis RB, Ettner SL, Appel S, Wilkey S, Van Rompay M, Kessler RC. Trends in alternative medicine use in the United States, 1990-1997: Results of a follow-up national survey. JAMA. (1998) 280:1569-75.

Kaptchuk TJ, Eisenberg DM. The persuasive appeal of alternative medicine. Ann Intern Med. (1998) 129:1061-5.

Kaptchuk TJ, Goldman P, Stone DA, Stason WB. Do medical devices have enhanced placebo effects? J Clin Epidemiol. (2000) 53:786-92.

Kaptchuk TJ. The double-blind, randomized, placebo-controlled trial: Gold standard or golden calf? J Clin Epidemiol. (2001) 54:541-9.

Eisenberg DM, Kessler RC, Van Rompay MI, Kaptchuk TJ, Wilkey SA, Appel S, Davis RB. Perceptions about complementary therapies relative to conventional therapies among adults who use both: Results from a national survey. Ann Intern Med. (2001) 135:344-51.

Kaptchuk TJ. Acupuncture: Theory, efficacy, and practice. Ann Intern Med. (2002) 136:374-83.

Kaptchuk TJ. The Placebo Effect in Alternative Medicine: Can the performance of a healing ritual have clinical significance? Ann Intern Med. (2002) 136:817-25.

Saper RB, Kales SN, Paquin J, Burns MJ, Eisenberg DM, Davis RB, Phillips RS. Heavy metal content of ayurvedic herbal medicine products. JAMA. (2004) 292:2868-73.

Yeh GY, Wood MJ, Lorell BH, Stevenson LW, Eisenberg DM, Wayne PM, Goldberger AL, Davis RB, Phillips RS. Effects of Tai Chi Mind-Body movement therapy on functional status and exercise capacity in patients with chronic heart failure: A randomized controlled trial. Am J Med. (2004) 117:541-8.

Kaptchuk TJ, Stason WB, Davis RB, Legedza AR, Schnyer RN, Kerr CE, Stone DA, Nam BH, Kirsch I, Goldman RH. Sham device v inert pill: Randomised controlled trial of two placebo treatments. BMJ. (2006) 332:391-7.

Kaptchuk TJ, Kelley JM, Conboy LA, Davis RB, Kerr CE, Jacobson EE, Kirsch I, Schyner RN, Nam BH, Nguyen LT, Park M, Rivers AL, McManus C, Kokkotou E, Drossman DA, Goldman P, Lembo AJ. Components of Placebo Effect: Randomised controlled trial in patients with irritable bowel syndrome. BMJ. (2008) 336:999-1003.