Recent Representative Publications of the Osher Center Leadership


Tick H, Nielsen A, Pelletier K, Bonakdar R, Simmons S, Glick R, Ratner E, Lemmon RL, Wayne P, Zador V, The Pain Task Force of the Academic Consortium for Integrative Medicine and Health. Evidence-Based Nonpharmacologic Strategies for Comprehensive Pain Care: The Consortium Pain Task Force White Paper. 2017.

Olenich S, Waterworth G, Crosby-Thompson A, Bensko J, Muskaj I, Badger GJ, Berrueta L, Levy B, Israel E, Langevin HM. Flexibility and strength training in asthma: A pilot study. Journal of Asthma (In Press).

Chaukos D, Chad-Friedman E, Mehta DH, Byerly L, Celik A, McCoy TH Jr, Denninger JW. SMART-R: A prospective cohort study of a resilience curriculum for residents by residents. Acad Psychiatry. 2017 Nov 2.

Zia FZ, Olaku O, Bao T, Berger A, Deng G, Yin Fan A, Garcia MK, Herman PM, Kaptchuk TJ, Ladas EJ, Langevin HM, Lao L, Lu W, Napadow V, Niemtzow RC, Vickers AJ, Shelley Wang X, Witt CM, Mao JJ. The National Cancer Institute’s Conference on Acupuncture for Symptom Management in Oncology: State of the science, evidence, and research gaps. J Natl Cancer Inst Monogr. 2017 Nov 1;2017(52).

Ellis R, Maheswaran R, Fox J, Hitt J, Langevin H, Henry S. Ultrasound elastography measurement of sciatic nerve displacement and shear strain during active and passive knee extension. Journal of Ultrasound in Medicine. In Press.

Song R, Ahn S, Lee M, Wayne PM, Sohn MK. Exploring the adaptability of Sun-style Tai Chi to stroke rehabilitation in Korean community dwelling stroke survivors: A mixed-methods feasibility study. Rehabilitation Nursing Journal. 2017. In Press.

Wayne PM, Lee MS, Osypiuk K, Ligibel J, Carlson LE, Song R. Tai Chi and Qigong for cancer-related symptoms and quality of life: A Systematic Review and Meta-Analysis. Journal of Cancer Survivorship. 2017. In Press.

Langevin HM, Bishop J, Maple R, Badger GJ, Fox JR. Effect of stretching on thoracolumbar fascia injury and movement restriction in a porcine model. American Journal of Physical Medicine and Rehabilitation. 2017. In Press.

Salmoirago-Blotcher E, Wayne PM, Dunsiger S, Krol J, Breault C, Bock BC, Wu WC, Yeh GY. Tai Chi Is a Promising Exercise Option for Patients With Coronary Heart Disease Declining Cardiac Rehabilitation. J Am Heart Assoc. 2017 Oct 11;6(10). pii: e006603.

Gow BJ, Hausdorff JM, Manor B, Lipsitz LA, Macklin EA, Bonato P, Novak V, Peng CK, Ahn AC, Wayne PM. Can Tai Chi training impact fractal stride time dynamics, an index of gait health, in older adults? Cross-sectional and randomized trial studies. PLoS One. 2017 Oct 11;12(10):e0186212. eCollection 2017.

Wayne PM, Lee MS, Osypiuk K, Ligibel J, Carlson LE, Song R. Tai Chi and Qigong for cancer-related symptoms and quality of life: A Systematic Review and Meta-Analysis. Journal of Cancer Survivorship. 2017. In Press.

Wayne PM, Yeh G, Mehta D. Minding the Mind-Body Literature: Focusing on Women’s Health and Pregnancy. The Journal of Alternative and Complementary Medicine. 2017 Sept; 23(9): 655-658.

Wayne PM, Gagnon MM, Macklin EA, Travison TG, Manor B, Lachman M, Thomas CP, Lipsitz LA. The Mind Body-Wellness in Supportive Housing (Mi-WiSH) study: Design and rationale of a cluster randomized controlled trial of Tai Chi in senior housing. Contemp Clin Trials. 2017 Sep;60:96-104. Epub 2017 Jul 8.

Wayne PM, Mehta D, Yeh G. Minding the Mind-Body Literature: Focusing on Veterans. J Altern Complement Med. 2017 Jun; 23(6):401-404.

Mehta D. Integrative Medicine and Cardiovascular Disorders. Prim Care. 2017 Jun; 44(2):351-367.

Carlson LE, Zelinski EL, Speca M, Balneaves LG, Jones JM, Santa Mina D, Wayne PM, Campbell TS, Giese-Davis J, Faris P, Zwicker J, Patel K, Beattie TL, Cole S, Toivonen K, Nation J, Peng P, Thong B, Wong R, Vohra S. Protocol for the MATCH study (Mindfulness and Tai Chi for cancer health): A preference-based multi-site randomized comparative effectiveness trial (CET) of Mindfulness-Based Cancer Recovery (MBCR) vs. Tai Chi/Qigong (TCQ) for cancer survivors. Contemp Clin Trials. 2017 May 30; 59:64-76.

Song, RN, Grabowska W, Park M, Osypiuk K, Vergara-Diaz G, Bonato P, Hausdorff JM, Fox M, Sudarsky LR, Macklin EA, Wayne PM. The impact of Tai Chi and Qigong mind-body exercises on motor and non-motor function and quality of life in Parkinson’s disease: A systematic review and meta-analysis. Parkinsonism & Related Disorders Parkinsonism Relat Disord. 2017 Aug;41:3-13. 2017.05.019. Epub 2017 May 25. Review.

Yeung AS, Feng R, Kim DJH, Wayne PM, Yeh GY, Baer L, Lee OE, Denninger JW, Benson H, Fricchione GL, Alpert J, Fava M. A Pilot, Randomized Controlled Study of Tai Chi With Passive and Active Controls in the Treatment of Depressed Chinese Americans. J Clin Psychiatry. 2017 May; 78(5):e522-e528.

Kandula N, Ahmed M, Dodani S, Gupta L, Hore P, Kanaya A, Khowaja A, Mathur A, Mehta D, Misra R, Paracha M, Bharmal N, Aghhi M, Leng J, Gany F. Cardiovascular disease & cancer risk among south asians: Impact of sociocultural influences on lifestyle and behavior. J Immigr Minor Health. 2017 May 10.

Cohen EM, Dossett ML, Mehta DH, Davis RB, Lee YC. Factors associated with complementary medicine use in pediatric musculoskeletal conditions: Results from a national survey. Complement Ther Med. 2017 Apr; 31:53-58.

Chaukos D, Chad-Friedman E, Mehta DH, Byerly L, Celik A, McCoy TH, Denninger JW. Risk and Resilience Factors Associated with Resident Burnout. Acad Psychiatry. 2017 Apr; 41(2):189-194.

Langevin HM, Schnyer RN. Reconnecting the Body in Eastern and Western Medicine. J Altern Complement Med. 2017 Apr; 23(4):238-241.

Wayne PM, Gloria Y. Minding the Mind-Body Literature: Focusing on Children and Youth. J Altern Complement Med. 2017 03; 23(3):155-157.

Stahl JE, Dossett ML, LaJoie AS, Denninger JW, Mehta DH, Goldman R, Fricchione GL, Benson H. Correction: Relaxation Response and Resiliency Training and Its Effect on Healthcare Resource Utilization. PLoS One. 2017; 12(2):e0172874.

Xiong Y, Berrueta L, Urso K, Olenich S, Muskaj I, Badger GJ, Aliprantis A, Lafyatis R, Langevin HM. Stretching Reduces Skin Thickness and Improves Subcutaneous Tissue Mobility in a Murine Model of Systemic Sclerosis. Front Immunol. 2017; 8:124.

Lauche R, Wayne PM, Fehr J, Stumpe C, Dobos G, Cramer H. Does Postural Awareness Contribute to Exercise-induced Improvements in Neck Pain Intensity? A Secondary Analysis of a Randomized Controlled Trial Evaluating Tai Chi and Neck Exercises. Spine (Phila Pa 1976). 2017 Jan 31.

Cohen EM, Morley-Fletcher A, Mehta DH, Lee YC. A systematic review of psychosocial therapies for children with rheumatic diseases. Pediatr Rheumatol Online J. 2017 Jan 17; 15(1):6.

Wayne P, Mehta D, Yeh G. Minding the Mind-Body Literature: Frontiers in Cancer Treatment. J Altern Complement Med. 2017 Jan; 23(1):4-7.



Ma Y, Dong M, Zhou K, Mita C, Liu J, Wayne PM. Publication Trends in Acupuncture Research: A 20-Year Bibliometric Analysis Based on PubMed. PLoS One. 2016; 11(12):e0168123.

Wayne PM, Yeh G, Mehta D. Minding the Mind-Body Literature. J Altern Complement Med. 2016 Nov; 22(11):849-852.

Eisenberg DM, Kaptchuk TJ, Post DE, Hrbek AL, O’Connor BB, Osypiuk K, Wayne PM, Buring JE, Levy DB. Establishing an Integrative Medicine Program Within an Academic Health Center: Essential Considerations. Acad Med. 2016 Sep; 91(9):1223-30.

Langevin HM, Keely P, Mao J, Hodge LM, Schleip R, Deng G, Hinz B, Swartz MA, de Valois BA, Zick S, Findley T. Connecting (T)issues: How Research in Fascia Biology Can Impact Integrative Oncology. Cancer Res. 2016; 76(21):6159-6162.

Engell S, Triano JJ, Fox JR, Langevin HM, Konofagou EE. Differential displacement of soft tissue layers from manual therapy loading. Clin Biomech (Bristol, Avon). 2016; 33:66-72.

Bishop JH, Fox JR, Maple R, Loretan C, Badger GJ, Henry SM, Vizzard MA, Langevin HM. Ultrasound Evaluation of the Combined Effects of Thoracolumbar Fascia Injury and Movement Restriction in a Porcine Model. PLoS One. 2016;11(1):e0147393.

Berrueta L, Muskaj I, Olenich S, Butler T, Badger GJ, Colas RA, Spite M, Serhan CN, Langevin HM. Stretching Impacts Inflammation Resolution in Connective Tissue.J Cell Physiol. 2016;231(7):1621-7.

Dossett ML, Korzenik JR, Baim M, Denninger JW, Mehta DH. A Case Report of Improvement in Crohn’s Disease-related Symptoms Following Participation in a Comprehensive Mind-Body Program. Glob Adv Health Med. 2016;5(1):122-5.

MacPherson H, Hammerschlag R, Coeytaux RR, Davis RT, Harris RE, Kong JT, Langevin HM, Lao L, Milley RJ, Napadow V, Schnyer RN, Stener-Victorin E, Witt CM, Wayne PM. Unanticipated Insights into Biomedicine from the Study of Acupuncture. J Altern Complement Med. 2016; 22(2):101-7.

Lauche R, Wayne PM, Dobos G, Cramer H. Prevalence, Patterns, and Predictors of T’ai Chi and Qigong Use in the United States: Results of a Nationally Representative Survey. J Altern Complement Med. 2016; 22(4):336-42.

Yeh GY, Chan CW, Wayne PM, Conboy L. The Impact of Tai Chi Exercise on Self-Efficacy, Social Support, and Empowerment in Heart Failure: Insights from a Qualitative Sub-Study from a Randomized Controlled Trial. PLoS One. 2016; 11(5):e0154678.

Lauche R, Stumpe C, Fehr J, Cramer H, Cheng YW, Wayne PM, Rampp T, Langhorst J, Dobos G. The Effects of Tai Chi and Neck Exercises in the Treatment of Chronic Nonspecific Neck Pain: A Randomized Controlled Trial. J Pain. 2016; 17(9):1013-27.

Budhrani-Shani P, Berry DL, Arcari P, Langevin H, Wayne PM. Mind-Body Exercises for Nurses with Chronic Low Back Pain: An Evidence-Based Review. Nurs Res Pract. 2016; 2016:9018036.

Yeh GY, Mu L, Davis RB, Wayne PM. Correlates of Exercise Self-efficacy in a Randomized Trial of Mind-Body Exercise in Patients With Chronic Heart Failure. J Cardiopulm Rehabil Prev. 2016 May-Jun; 36(3):186-94.



Langevin HM, Schnyer R, MacPherson H, Davis R, Harris RE, Napadow V, Wayne PM, Milley RJ, Lao L, Stener-Victorin E, Kong JT, Hammerschlag R. Manual and electrical needle stimulation in acupuncture research: pitfalls and challenges of heterogeneity. J Altern Complement Med. 2015; 21(3):113-28.

Jacobson EE, Meleger AL, Bonato P, Wayne PM, Langevin HM, Kaptchuk TJ, Davis RB. Structural integration as an adjunct to outpatient rehabilitation for chronic nonspecific low back pain: a randomized pilot clinical trial. Evid Based Complement Alternat Med. 2015; 2015:813418.

Wayne PM, Hausdorff JM, Lough M, Gow BJ, Lipsitz L, Novak V, Macklin EA, Peng CK, Manor B. Tai Chi Training may Reduce Dual Task Gait Variability, a Potential Mediator of Fall Risk, in Healthy Older Adults: Cross-Sectional and Randomized Trial Studies. Front Hum Neurosci. 2015; 9:332.

Salmoirago-Blotcher E, Wayne PM, Bock BC, Dunsiger S, Wu W, Stabile L, Yeh G. Design and methods of the Gentle Cardiac Rehabilitation Study – A behavioral study of tai chi exercise for patients not attending cardiac rehabilitation. Contemp Clin Trials 2015;43:243-51.

Moy ML, Wayne PM, Litrownik D. Beach D, Klings ES, Davis EB, Yeh GY. Long-term Exercise After Pulmonary Rehabilitation (LEAP):  design and rationale of a randomized controlled trial of Tai Chi Contemporary Clinical Trials, 2015;45(Pt B):458-67.

Gow B, Peng CK, Wayne PM, Ahn A. Multiscale entropy analysis of center-of-pressure dynamics in human postural control: methodological considerations.  Entropy 2015;17: 7926–7947.

Walsh JN, Manor B,  Hausdorff J, Novak V, Lipsitz L, Gow B, Macklin EA, Peng CK,   Wayne PM.   Impact of short- and long-term Tai Chi mind-body exercise training on cognitive function in healthy adults: Results from a hybrid observational study and randomized trial.  Global Adv Health Med. 2015;4:38-48.

O’Connor B, Eisenberg DM, Buring JE, Liang C, Osypiuk K, Levy DB, Wayne PM. Within-team Patterns of Communication and Referral in Multimodal Treatment of Chronic Low Back Pain Patients by an Integrative Care Team.  Global Adv Health Med 2015;4:36-45.

Yang GY, Wang LQ, Ren J, Zhang Y, Li ML, Zhu YT, L Juo, Cheng YJ, Li WY, Wayne PM, Liu JP. Evidence Base of Clinical Studies on Tai Chi: A Bibliometric Analysis.  PLoS ONE 2015;10(3):e0120655.

Miller KM, Chad-Friedman E, Haime V, Mehta DH, Lepoutre V, Gilburd D, Peltier-Saxe D, Lilley C, Benson H, Fricchione GL, Denninger JW, Yeung A. The effectiveness of a brief mind-body intervention for treating depression in community health center patients. Glob Adv Health Med. 2015;4(2):30-5.

Sylvia LG, Bui E, Baier AL, Mehta DH, Denninger JW, Fricchione GL, Casey A, Kagan L, Park ER, Simon NM. Resilient Warrior: A Stress Management Group to Improve Psychological Health in Service Members. Glob Adv Health Med. 2015;4(6):38-42.

Stahl JE, Dossett ML, LaJoie AS, Denninger JW, Mehta DH, Goldman R, Fricchione GL, Benson H. Relaxation Response and Resiliency Training and Its Effect on Healthcare Resource Utilization. PLoS One. 2015;10(10):e0140212.

Scult M, Haime V, Jacquart J, Takahashi J, Moscowitz B, Webster A, Denninger JW, Mehta DH. A healthy aging program for older adults: effects on self-efficacy and morale. Adv Mind Body Med. 2015;29(1):26-33.

Perez GK, Haime V, Jackson V, Chittenden E, Mehta DH, Park ER. Promoting resiliency among palliative care clinicians: stressors, coping strategies, and training needs. J Palliat Med. 2015 Apr;18(4):332-7.


Seminal Publications of the Osher Center for Integrative Medicine

Eisenberg DM, Kessler RC, Foster C, Norlock FE, Calkins DR, Delbanco TL. Unconventional medicine in the United States. Prevalence, costs, and patterns of use. N Engl J Med. 1993; 328(4):246-52.

Eisenberg DM, Davis RB, Ettner SL, Appel S, Wilkey S, Van Rompay M, Kessler RC. Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA. 1998; 280(18):1569-75.

Kaptchuk TJ, Eisenberg DM. The persuasive appeal of alternative medicine. Ann Intern Med. 1998 Dec 15; 129(12):1061-5.

Kaptchuk TJ, Goldman P, Stone DA, Stason WB. Do medical devices have enhanced placebo effects? J Clin Epidemiol. 2000; 53(8):786-92.

Kaptchuk TJ. The double-blind, randomized, placebo-controlled trial: gold standard or golden calf? J Clin Epidemiol. 2001; 54(6):541-9.

Eisenberg DM, Kessler RC, Van Rompay MI, Kaptchuk TJ, Wilkey SA, Appel S, Davis RB. Perceptions about complementary therapies relative to conventional therapies among adults who use both: results from a national survey. Ann Intern Med. 2001; 135(5):344-51.

Kaptchuk TJ. Acupuncture: theory, efficacy, and practice. Ann Intern Med. 2002; 136(5):374-83.

Kaptchuk TJ. The placebo effect in alternative medicine: can the performance of a healing ritual have clinical significance? Ann Intern Med. 2002 Jun 4; 136(11):817-25.

Saper RB, Kales SN, Paquin J, Burns MJ, Eisenberg DM, Davis RB, Phillips RS. Heavy metal content of ayurvedic herbal medicine products. JAMA. 2004 Dec 15; 292(23):2868-73.

Yeh GY, Wood MJ, Lorell BH, Stevenson LW, Eisenberg DM, Wayne PM, Goldberger AL, Davis RB, Phillips RS. Effects of tai chi mind-body movement therapy on functional status and exercise capacity in patients with chronic heart failure: a randomized controlled trial. Am J Med. 2004; 117(8):541-8.

Kaptchuk TJ, Stason WB, Davis RB, Legedza AR, Schnyer RN, Kerr CE, Stone DA, Nam BH, Kirsch I, Goldman RH. Sham device v inert pill: randomised controlled trial of two placebo treatments. BMJ. 2006 Feb 18; 332(7538):391-7.

Kaptchuk TJ, Kelley JM, Conboy LA, Davis RB, Kerr CE, Jacobson EE, Kirsch I, Schyner RN, Nam BH, Nguyen LT, Park M, Rivers AL, McManus C, Kokkotou E, Drossman DA, Goldman P, Lembo AJ. Components of placebo effect: randomised controlled trial in patients with irritable bowel syndrome. BMJ. 2008; 336(7651):999-1003.